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Medical, health, and genomics

Digital pathology helps decode tumor microenvironments for precision immunotherapy. GigaPath is a novel vision transformer that can scale to gigapixel whole-slide images by adapting dilated attention for digital pathology. In joint work with Providence and UW, we’re sharing Prov-GigaPath, the first whole-slide pathology foundation model pretrained on large-scale real-world data, for advancing clinical research and discovery.

GigaPath: Whole-Slide Foundation Model for Digital Pathology

Research Forum Ep2 | Panel | Transforming the Natural Sciences with AI

Research Forum 2 | Panel Discussion: Transforming the Natural Sciences with AI

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Scaling early detection of esophageal cancer with AI

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Microsoft Health Futures

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Published Date

Podcast

The reality of generative AI in the clinic

March 20, 2025

UC San Diego Health’s Dr. Christopher Longhurst and UC San Francisco Health’s Dr. Sara Murray explore how generative AI is changing patient care, clinical workflows, and decision-making and how they envision the technology impacting the…

AI Revolution podcast | Episode 1 - The reality of generative AI in the clinic | outline illustration of Dr. Sara Murray, Peter Lee, Dr. Christopher Longhurst

Publication

Evidence Aggregator: AI reasoning applied to rare disease diagnostics

Hope Twede, Ashley Conard, Lynn Pais, Samantha Brye, Emily O’Heir, Greg Smith, Ron Paulsen, Christina A. Austin-Tse, Alex Bloemendal, Cas Simons, Scott Saponas, Miah Wander, Daniel G. MacArthur, Heidi Rehm

March 2025

Podcast

The AI Revolution in Medicine, Revisited: An Introduction

March 6, 2025

Host Peter Lee, Microsoft Research president, discusses the motivation behind the new series and the GPT-4 encounter that helped him view the tech not only as a potential tool for improving healthcare but a chance…

AI Revolution podcast | Episode 0 - A brief introduction from Peter Lee | outline illustration of Peter Lee

Microsoft Research Blog

Advancing biomedical discovery: Overcoming data challenges in precision medicine

March 5, 2025 | Mandi Hall

Our recent study in Nature Scientific Reports identified key challenges in the biomedical data lifecycle and offered 7 actionable recommendations.

white line icon of a medical paper and of a computer with a person in front of it on a blue and green gradient background

Publication

Deep learning guided design of protease substrates

Carmen Martin-Alonso, Sarah Alamdari, Tahoura S. Samad, Kevin Kaichuang Yang, Sangeeta N. Bhatia, Ava P. Amini

bioRxiv | March 2025

Publication

Scalable Universal T-Cell Receptor Embeddings from Adaptive Immune Repertoires

Paidamoyo Chapfuwa, Ilker Demirel, Lorenzo Pisani, Javier Zazo, Elon Portugaly, H. Jabran Zahid, Julia Greissl

ICLR 2025 | March 2025

Github

Publication

Rapid and accurate prediction of protein homo-oligomer symmetry using Seq2Symm

Meghana Kshirsagar, Artur Meller, Ian R. Humphreys, Samuel Sledzieski, Yixi Xu, Rahul Dodhia, Eric Horvitz, Bonnie Berger, Gregory R. Bowman, Juan M. Lavista Ferres, David Baker, Minkyung Baek

Nature Communications | February 2025

Project

Video

AI for Precision Health: Learning the language of nature and patients

February 25, 2025 | Hoifung Poon, Ava Amini, Lili Qiu, Matthew Lungren, Carlo Bifulco

Hosted by Hoifung Poon, with Lili Qiu, Ava Amini, Carlo Bifulco (opens in new tab), and Matthew Lungren at Microsoft Research Forum, Episode 5 This panel discussion with Microsoft researchers and external guests explores the transformative potential of generative AI in…

44:59

Video

Keynote: Multimodal Generative AI for Precision Health

February 25, 2025 | Hoifung Poon

Presented by Hoifung Poon at Microsoft Research Forum, Episode 5 Hoifung Poon, General Manager of Microsoft Health Futures, introduces an agenda in precision health, utilizing generative AI to pretrain high-fidelity patient embeddings from multimodal, longitudinal patient journeys. This…

17:14

Event

Microsoft Research Forum

February 25, 2025 | Virtual

Microsoft Research Forum Location: Virtual Microsoft Research Forum is a virtual series highlighting purposeful research and its real-world impact, from fundamental exploration to advancing AI responsibly, scaling innovation through products and open source, and driving…

Medical, health, and genomics

Highlights